Dissemination will occur through peer-reviewed journals and an integrated knowledge translation plan. Parents of participants will provide written consent. The brain's surface is fairly smooth, typical for a 'primitive' animal. Ethics and dissemination The KOALA study is approved by the Sainte-Justine University Hospital, McGill University Health Centre and University of Calgary Conjoint Health Research Ethics Boards. The koala has one of the smallest brains in proportion to body weight of any mammal,: 81 being 60 smaller than that of a typical diprotodont, weighing only 19.2 g (0.68 oz) on average. A combination of child, injury, socioenvironmental and psychobiological factors are expected to predict behaviour and quality of life at 1, 3 and 12 months postinjury. Group comparisons and predictive models will test the a priori hypotheses that, compared with children from the community or with orthopaedic injuries, children with mTBI will (1) display more postconcussive symptoms and exhibit poorer motor, cognitive, social and behavioural functioning (2) show evidence of altered brain structure and function, poorer sleep and higher levels of stress hormones. Biological measures, including measures of brain structure and function (magnetic resonance imaging, MRI), stress (hair cortisol), sleep (actigraphy) and genetics (saliva), will complement direct testing of function using developmental and neuropsychological measures and parent questionnaires. See how it works 3D room Avatars Video-call Teacher Controls In Koala, the teacher has full control over what actions the students can and can't do. A comprehensive battery of prognostic and outcome measures will be collected in the PED, at 10 days, 1, 3 and 12 months postinjury. Koala is a fun and collaborative learning space where your students will excel and flourish. Children who sustain mTBI (n=150) or an orthopaedic injury (n=75) will be recruited from three paediatric emergency departments (PEDs), and compared with typically developing children (community controls, n=75). Methods and analyses KOALA is a prospective, multicentre, longitudinal cohort study of children aged 6 months to 6 years at the time of injury/recruitment. The objective of the Kids’ Outcomes And Long-term Abilities (KOALA) study is to document the impact of early mTBI on children’s motor, cognitive, social and behavioural functioning, as well as on quality of life, stress, sleep and brain integrity. Not all animals have neurons Trichoplax and sponges lack nerve cells altogether. ![]() However, little research focuses on the consequences of mTBI early in development. Overview Neurons are the cells that transmit information in an animal 's nervous system so that it can sense stimuli from its environment and behave accordingly. Koalas are amongst the least intelligent mammals due to their small brains and eating toxic eucalyptus trees that damage their brains over their natural. Introduction Mild traumatic brain injury (mTBI) is highly prevalent, especially in children under 6 years.
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